General Information

  • ID:  hor000323
  • Uniprot ID:  NA
  • Protein name:  Allatostatin C
  • Gene name:  NA
  • Organism:  Cancer borealis
  • Family:  Allatostatin family
  • Source:  Animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  SYWKQCAFNAVSCF
  • Length:  14
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Inhibited the frequency of the pyloric rhythm of the STG
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor000323_AF2.pdbhor000323_ESM.pdb

Physical Information

Mass: 188595 Formula: C76H104N18O20S2
Absent amino acids: DEGHILMPRT Common amino acids: ACFS
pI: 8.22 Basic residues: 1
Polar residues: 6 Hydrophobic residues: 6
Hydrophobicity: 26.43 Boman Index: -616
Half-Life: 1.9 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 35
Instability Index: 3669.29 Extinction Coefficient cystines: 7115
Absorbance 280nm: 547.31

Literature

  • PubMed ID:  19505516
  • Title:  Mass Spectrometric Characterization and Physiological Actions of Novel Crustacean C-type Allatostatins